Project Area B

Induction of pluripotency by nuclear reprogramming

Prof. Dr. Magdalena Götz with Dr. Benedikt Berninger
Project Title: Role of Sox2 in the direct lineage reprogramming of astroglia and pericytes into neurons

Dr. Michele Boiani
Project Title:
Exploring novel molecular tools and strategies to analyze pluripotency induction in somatic cells and to derive factor-free iPS cells

Dr. Frank Edenhofer
Project Title: Exploring novel molecular tools and strategies to analyze pluripotency induction in somatic cells and to derive factor-free iPS cells

Dr. Takashi Hiiragi
Project Title: Molecular mechanism of natural pluripotency establishment in the early mouse embryo based on single-cell gene expression profile

Prof. Dr. Heinrich Leonhardt
Project Title: dTALEs as a tool for targeted transcriptional activation and recruitment of epigenetic modifiers

Dr. Jessica Nolte (Prof. Dr. Wolfgang Engel) and Dr. Ulrich Zechner
Project Title:
Characterization of the putative pluripotency-regulating genes Lrrc34 and Zfp819

Prof. Dr. Renato Paro
Project Title: Epigenetic Control of Regeneration and Transdetermination in Drosophila imaginal discs

Prof. Dr. Hans Robert Schöler and Dr. Nishant Singhal
Project Title: Identification of additional/alternative factors required for cellular reprogramming

Prof. Dr. Elly M. Tanaka
Project Title: Analysis of conserved pluripotency network in Axolotl

Prof. Dr. Jörn Walter
Project Title: DNA demethylation in zygotes

Prof. Dr. Martin Zenke
Project Title: Reprogramming and somatic memory in ES cell/hematopoietic cell hybrids

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Funding Programme:

SPP 1356 Coordinator:
Prof. Dr. Albrecht Müller

Steering Committee:
Prof. Dr. Hans Robert Schöler
Prof. Dr. Jörn E. Walter
Prof. Dr. Martin Zenke