Project Area A

Genetic and epigenetic networks that control pluripotency

Dr. Konstantinos Anastassiadis
Project Title: The role of chromatin modifications in the efficiency of reprogramming after nuclear transfer and after exposure of differentiated cells to exogenous factors

Prof. Dr. Peter Becker
Project Title: Contributions of chromatin remodelling factors CHRAC/ACF to epigenome programming during oogenesis and early embryogenesis in Drosophila melanogaster

Prof. Dr. Maria Cristina Cardoso
Project Title: Role of methyl-cytosine binding proteins in the gain and loss of pluripotency

Dr. Heiko Lickert, Prof. Dr. Gunnar Schotta
Project Title: Epigenetic mechanisms that define the exit from pluripotency

Prof. Dr. Albrecht M. Müller
Project Title: Functional analyses and chromatin studies of embryonic stem cell pluripotency by reversible knockdown of Bmi1 paralogs of Polycomb repressive complex 1 (PRC1).

Prof. Dr. Gunter Reuter
Project Title: Epigenetic control of pluripotency in Drosophila primordial and ovarian germ line stem cells

Prof. Dr. Karl-Lenhard Rudolph
Project Title: The role of p53 dependent and cooperating pathways in pluripotency induction

Dr. Timm Schroeder
Project Title: Visualisation of transcription factor network dynamics in living stem cells

Jens C. Schwamborn
Project Title: Function of cell fate determinants during acquisition and loss of pluripotency.

Prof. Dr. Adrian Francis Stewart
Project Title: Robust model systems for analyzing the reprogramming of somatic cells into pluripotent cells

Prof. Dr. Mathias Treier
Project Title: The role of the H3K9 demethylase Jmjd1c in embryonic stem cell self-renewal and pluripotency

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Funding Programme:

SPP 1356 Coordinator:
Prof. Dr. Albrecht Müller

Steering Committee:
Prof. Dr. Hans Robert Schöler
Prof. Dr. Jörn E. Walter
Prof. Dr. Martin Zenke