Jobs

Postdoctoral position in Munich - Epigenetic mechanisms that define the exit from pluripotency

Description:

A postdoctoral position is available in the context of the German Priority Program SPP1356 “Pluripotency and Reprogramming” to study epigenetic processes that define and regulate the exit from pluripotency.

The research in our group focuses on the functional analysis of histone modifications in the mouse. In particular, we use knock-out mice to study the functions of histone methyltransferases for normal and aberrant development. Our methods cover the whole field of modern cell and molecular biology/biochemistry such as protein purification, immunofluorescence, ChIP-seq, generation and characterisation of antibodies, quantitative PCR, microarrays as well as mouse genetics, histology and FACS analysis.

Qualifications:

Candidates will be highly motivated to carry out an independent research project in tight connection with collaborating laboratories. A PhD with a strong research background in molecular biology is required. Expertise in chromatin immunoprecipitation (ChIP-qPCR, ChIP-seq) is strongly preferred.

Salary Details: Payment is according to the Federal payment scheme (E13).

Application Details: please send your application (CV, details about previous work, 2 reference letters) to:

Prof. Dr. Gunnar Schotta
Adolf-Butenandt-Institute
- Molecular Biology -
Schillerstr. 44
80336 Munich

Gunnar.Schotta@med.uni-muenchen.de

http://www.molekularbiologie.abi.med.uni-muenchen.de/ueber_uns/schotta/index.html

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Postdoc Position at the MDC in Berlin

Disabled persons are given preference given the same qualification.

The MDC strives to employ a higher proportion of women and encourages qualified women to apply.

Please, only submit copies as we do not return the application documents.

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Post-Doc in Stem Cell Biology (Molecular Biology / Cell Biology) in Bonn

Applications are invited for a position of a Postdoctoral Research Scientist to join the well-equipped Stem Cell Engineering Group at the Department of Reconstructive Neurobiology, University of Bonn. The research project focuses on cellular reprogramming and basic embryonic stem cell biology (Nolden et al., Nature Methods. 2006 Jun;3(6):461; Bosnali M, Edenhofer F., Biol Chem. 2008 Jul;389(7):851; Patsch et al., Stem Cells 2010 Jul;67(14):2439-49.

Research will involve the development of non-genetic technologies for cellular reprogramming of somatic cells to multi- or pluripotency and the analysis of molecular mechanisms underlying nuclear reprogramming at the molecular and cellular level. Novel non-genetic and biochemical technologies will be applied in order to functionally screen for factors that are involved in cellular reprogramming.

The successful applicant should have a PhD or MD/PhD with a strong background in cell biology. Previous experience in at least one of the following areas is essential: cultivation of pluripotent human or mouse ES cells; retro- or lentiviral transduction, recombinant protein expression.

Self-motivation, enthusiasm, and creativity is expected. You should be able to supervise a PhD student and and technician. You will benefit from working in a stimulating interdisciplinary environment encompassing a wide spectrum of modern stem cell biology. We are providing excellent working and laboratory conditions in a newly established laboratory.

Applicants should send a CV, including a list of publications, the names and addresses of two academic referees as well as a summary of area of interests and future plans to:

PD Dr. Frank Edenhofer, Institute of Reconstructive Neurobiology, University of Bonn, Sigmund-Freud-Strasse 25, 53105 Bonn ***  email-applications are preferred: f.edenhofer@uni-bonn.de

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